What is systemic lupus erythematosus?
Lupus is an autoimmune disease identified by acute and chronic irritation of various tissues of the body. Autoimmune diseases are syndrome that arise when the body’s tissues are attacked by its own immune system. The immune system is a difficult system within the body that is designed to fight infectious agents, such as bacteria and other foreign microbes. One of the ways that the immune system fights infections is by generating antibodies that bind to the microbes. People with lupus create abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. These antibodies are referred to as autoantibodies.
lnflammation can affect tissues anywhere in the body, Because of the antibodies and accompanying cells.Lupus has the potential to affect a variation of areas. Sometimes lupus can root disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is concerned by rash, the condition is called lupus dermatitis or cutaneous lupus erythematosus. A form of lupus dermatitis that can be remote to the skin, without internal disease, is called discoid lupus erythematosus. When internal organs are occupied, the condition is referred to as systemic lupus erythematosus (SLE).
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Both discoid lupus erythematosus and systemic lupus are more general in women than men (about eight times more common). The disease can involve all ages but most commonly begins from 20-45 years of age. Statistics demonstrate that lupus is somewhat more common in African Americans and people of Chinese and Japanese descent.